The name of a character in the film Trainspotting, played by Jonny Lee Miller. Sick Boy is noted for having a fondness for James Bond/Sean Connery trivia and quotes, dressing well and always having something pertinent to say.

Like most of the other main characters in the film, Sick Boy is a heroin addict, but as he demonstrates (the "Sick Boy method"), he can kick his habit without much apparent trouble. He and fellow addict Alison had a baby daughter named Dawn.