I once had a user complain that her computer would just randomly do weird things when she was just sitting there doing nothing. I could not figure it out until I went to her office.

I tested the keyboard but was unable to duplicate the problem. However as soon as I had her sit at her desk the problem became clear. She had huge breasts that hung down and rested on the keyboard; using heroic restraint to keep from laughing out loud, I as diplomatically as possible explained the cause of her problems.