A movie by Ed Wood, it is about transvestitism and transexuality. Ed Wood was a transvestite himself, and tried to make a serious movie on these topics. Narrated by Bela Lugosi, I think that it is even worse than Plan 9 from Outer Space.

Glen or Glenda. Ed Wood's first film was an autobiography. The alternate title of Look Back in Angora was never considered but should have been.